NIH NIDA Presolicitation: Brain Development Cohorts Data Sharing Platform

Notice ID: 75N95024Q00035

The Government is seeking Capability Statements on behalf of The National Institute on Drug Abuse (NIDA) from Business organizations under the North American Industry Classification System (NAICS) code 518210, that can provide a scalable data sharing platform according to anticipated future needs as the data collection grows and potential new use cases arise for NIDA’s ABCD study as well as other potential datasets. This data sharing platform shall include project management, data analytics, operations, database, and data analytics support, software engineering, managing a help desk, infrastructure support to the research community who are trying to deposit or access data, scientific support to program staff and other federal employees, and quality assurance checks on the data provided.

The platform will provide a data sharing ecosystem for large, population neuroscience studies such as the Adolescent Brain Cognitive Development (ABCD) Study. The ABCD Study® is an ongoing longitudinal study that is following the development of youth enrolled when they were 9-10 years of age and followed until they are 19-20 years old. The ABCD Study has been collecting multi-modal data and making those data available with the research community since 2018 (the study launched in 2016).

Multi-modal longitudinal research data is being continuously gathered from nearly 12,000 individual participants of the ABCD Study for the research community to mine and analyze to provide new knowledge related to adolescent brain development.  The current database used for storage and dissemination of data is no longer capable of supporting the growing dataset and the increased demand for access to the data. The ABCD Study needs a data sharing platform capable of facilitating in situ computations of complex data sets, instead of only supporting download of multiple copies of the data and thereby increasing security risks and expenses. The ABCD program seeks to transfer the entire data collection to a more capable and robust platform that will securely store the data while also providing an easily accessible workspace from which data can be processed and analyzed using a variety of data analysis tools.  As a repository holding de-identified human subjects research data, the data sharing platform must efficiently comply with all relevant federal regulations related to security and research subject privacy.  The platform must also have the capacity to support additional multimodal data from the HBCD Study, a population neuroscience study of infant and early childhood development.

PROJECT REQUIREMENTS:

Capable vendors shall demonstrate expertise in managing and expanding a research infrastructure that will be responsible for hosting the storage and access of multiple research data types from the ABCD Study, and other large datasets. This includes, but is not limited to, demonstrating the capability to share de-identified data from minimally, 12,000 research participants and the capability of storing at least 200 terabytes of data within a single infrastructure. Interested small business organizations must demonstrate the required capabilities and in-depth knowledge in the areas listed below:

Project Management. Capable vendors must demonstrate their experience and expertise with providing overall project management of health science data sharing platform, with past experience in ensuring that the technical and operational implementation meets the scientific, technical, and program needs of NIDA. Interested vendors should demonstrate the capability to = extend the existing infrastructure to establish and maintain an improved centralized data management, tracking, and distribution platform capable of providing secure storage, analysis, curation, and public access of raw/derived data. Interested parties should describe their approach to ensuring that NIH data sharing policies and standard operating procedures are followed. Additionally, past experience in research infrastructure is requested to demonstrate the capability to participate in scientific and technical presentations and panels as requested by the NIH in their efforts to meet project specific goals.

Operation and Database Support. Capable vendors should demonstrate their ability to perform system base installation, configuration and implementation for the NIH data sharing platform. Once established, the platform will be hosted in the Cloud and use Single Sign On with 2-factor authentication. Vendors must demonstrate their capability to scale, tune and optimize the platform to accommodate approximately 3,000 users per year with full operation, monitoring and maintenance.  This includes providing support for a help desk and training videos for users. Interested vendors must demonstrate their capability to provide ABCD specific branding and customization of the portal, and additional study branding as needed, to support user-level and administrative-level dashboards and messaging system configurations.  Capable vendors should describe their approach for making the platform available to the research community 99.5% of the time, exclusive of planned maintenance and upgrades being installed. Interested vendors shall describe their capability to implement and maintain a disaster recovery plan utilizing Cloud services and/or NIH internal disaster recovery capabilities…

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