Notice ID 75N95024Q00032
The Longitudinal Study Section (LSS) in the TGB conduct several clinical and epidemiological studies aimed at the Baltimore Longitudinal Study of Aging (BLSA), America’s longest-running scientific study of human aging which began in 1958. The focus of the study is to characterize how an individual ages across the adult life span and individuals have been continually recruited for participation since its initiation. The study measures and interprets data in several health subjects, including cardiovascular health.
Project Requirements:
Independently and not as an agent of the Government, the Contractor shall furnish all the necessary services, qualified personnel, material, equipment, and facilities, not otherwise provided by the Government as needed to the following specific requirements:
Provide expertise and consultation concerning ongoing research and clinical projects within the IRP.
Provide input on scientific efforts being pursued within the IRP, especially competitive opportunities such as interlaboratory projects proposal and internal grants submitted by IRP investigators.
Technical guidance and direct assistance in writing and editing of meeting abstracts, internal documents, IRP communications, manuscripts, and funding proposals.
Contribute to the conceptualization, writing and editing of scientific protocols on issues related to aging and aging biology both in animal models and humans.
Conduct literature searches and identify critical references for documentation and scientific articles.
Search for technological solutions to scientific questions related to aging and age-related diseases, in particular concerning the BLSA and other clinical studies conducted by LSS.
The contractor shall contribute directly to the ongoing study of Application of DNA repair capacity assays to assess DNA repair activity changes with age in the BLSA and GESTALT studies.
Review project on Alternate RNA splicing as part of a resilience mechanism in aging. Providing written materials from background searches, discussion of ideas and concepts, organize concepts into a cohesive plan and assist with manuscript preparation and editing. Manuscript in preparation titled: Resilience to age-related impairment of mitochondrial function through alternative pre-mRNA splicing.
Attend and provide written synopsis of NIA Strategic Planning Meeting.
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